Search results for "viral epitope"

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Phylodynamic Analysis and Implication of HCV Genotype 4 Variability on Antiviral Drug Response and T-Cell Recognition.

2020

Therapies for HCV care could change the prevalence and the geographic distribution of genotypes due to differences in Sustained Virologic Response (SVR). In this scenario, uncommon genotypes/subtypes, such as genotype 4, could spread from high-risk groups, replacing genotypes eradicated by antiviral drugs. Genotype eradication is also strongly influenced by the CD8+ T cell response. In this study, the genetic variability in HCV genotype 4 strains obtained from a cohort of 67 patients na&iuml

Settore MED/07 - Microbiologia E Microbiologia ClinicaT-Lymphocyteslcsh:QR1-502Bayesian analysisHepacivirusViral Nonstructural Proteinslcsh:MicrobiologyCoalescent theoryphylodynamicGenotypegenetic variabilityPhylogenyBayesian analysimedia_commonSettore MED/12 - Gastroenterologiavirus diseasesMiddle Agedviral epitopeHepatitis CHost-Pathogen InteractionInfectious Diseasesmedicine.anatomical_structureHost-Pathogen InteractionsHCVtMRCADrugAdultGenotypemedicine.drug_classmedia_common.quotation_subjectT cellmacromolecular substancesHuman leukocyte antigenBiologyAntiviral AgentsArticleYoung AdultT cell recognitionVirologyDrug Resistance ViralmedicineHumansGenetic variabilitygenotype 4AgedDAAAntiviral AgentHepaciviruVirologydigestive system diseasesviral epitopesAntiviral drugCD8RASViruses
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